(1) Background.Snake venom phosphodiesterases (SVPDEs) are among the least studied venom enzymes.In envenomation, they display various pathological effects, including induction of hypotension, inhibition of platelet aggregation, edema, and paralysis.Until now, there have been no 3D structural studies of these enzymes, thereby preventing structure&#
The link between reported cases of COVID-19 and the Infodemic Risk Index: A worldwide perspective
In this brief report we followed the evolution of the COVID-19 Infodemic Risk Index during 2020 and clarified its connection with the Coolers epidemic waves, focusing specifically on their co-evolution in Europe, South America, and South-eastern Asia.Using 640 million tweets collected by the Infodemic Observatory and the open access dataset publish
Children diagnosed with congenital cardiac malformations at the national university departments of pediatric cardiology: positive predictive values of data in the Danish National Patient Registry
Peter Agergaard1, Anders Hebert2, Jesper Bjerre3, Karina Meden Sørensen4, Charlotte Olesen3, John HDMI Coupler Rosendal Østergaard31Department of Pediatrics, Viborg Hospital, Viborg, Denmark; 2Department of Pediatrics, Copenhagen University Hospital, Rigshospitalet, Denmark; 3Department of Pediatrics, Aarhus University Hospita
Vaccination of cattle with synthetic peptides corresponding to predicted extracellular domains of Rhipicephalus (Boophilus) microplus aquaporin 2 reduced the number of ticks feeding to repletion
Abstract Background There have been ongoing efforts to identify anti-tick vaccine targets to protect cattle from infestation with cattle fever ticks Rhipicephalus (Boophilus) microplus.Two commercial vaccines based on the tick gut protein Bm86 have had variable effectiveness, which has led to poor acceptance, and numerous studies have attempted to